Quantity: ~1M viable cells
CIRM Line ID: CW50115
Disease: Alzheimer’s Disease
Gender: Female
Sampled age: 67
Ethinicity: Caucasian, Latino
Description
Quantity: ~1M viable cells
CIRM Line ID: CW50115
Disease: Alzheimer’s Disease
Gender: Female
Sampled age: 67
Race: Caucasian, Latino
Donor data
Demographic (source: CIRM) | Description | ALZHEIMER DISEASE; AD |
Affected Status | Yes | |
Product | iPSC | |
Source | PBMC | |
Sex | Female | |
Age at Sampling | 67 YR | |
Race | Caucasian | |
Ethnicity | Hispanic or Latino | |
Publications Cited | 0 | |
dbGap | No | |
Biopsy Source | Blood | |
Collection | Alzheimer’s Disease | |
Cell Type | Stem Cell | |
Tissue Type | Induced pluripotent stem cell | |
Transformant | Episomal | |
Species | sapiens | |
Common Name | human | |
Detailed Clinical Data | false | |
Clinical data (source: CIRM) | AlzheimersDisease | AlzheimersDisease |
Typical_probable_AD_diagnosis | Yes | |
Age_at_onset_of_dementia | 58 | |
Atypical_probable_AD:_Progressive aphasia | No | |
Atypical_probable_AD:_Posterior cortical_atrophy | No | |
APOE_e4_carrier | Yes | |
Amyloid_biomarker_test_conducted_(CSF_or_amyloid_P | Yes | |
Height_(inches) | 59 | |
Weight_(pounds) | 136 |
- Users do not need any additional license for the use of these differentiated cells even when cells are used for high throughput screening or drug discovery.
- All donor consents include statements on the following:
- Testing the cells’ DNA (this is referred to as the cell’s genetic code or sequence) and making the information known to other researchers
- Changing some of the genetic code or sequence within these cells
- Using cells to test or select drugs to treat disease
- Transplanting cells or resulting products to humans or animals
Distributing cells widely (nationally and internationally) for research, training or commercial medical product development - Future research and uses unforeseen at this time
- Donors were screened and negative for HIV, HBV, and HCV. Donors under the age of 18 could opt out of HIV testing; all HCV-positive donors submitted skin punches, not peripheral blood, and were not screened for any infectious agents due to small volume of blood present in punches.
- Human induced pluripotent stem cells were established by non-integrating episomal reprogramming. Reprogramming and quality control were performed by Cellular Dynamics International.
Characteristics
Please refer this page for some characteristics data.