Name: GABAergic Neurons from Alzheimer's Disease (CW50115, F, 67, Caucasian, Latino)
SKU: GA-SeV-CW50115
Availability: OutOfStock

Quantity: ~1M viable cells
CIRM Line ID: CW50115
Disease: Alzheimer’s Disease
Gender: Female
Sampled age: 67
Ethinicity: Caucasian, Latino

Description

Quantity: ~1M viable cells
CIRM Line ID: CW50115
Disease: Alzheimer’s Disease
Gender: Female
Sampled age: 67
Race: Caucasian, Latino

Donor data

Demographic (source: CIRM)	Description	ALZHEIMER DISEASE; AD
	Affected Status	Yes
	Product	iPSC
	Source	PBMC
	Sex	Female
	Age at Sampling	67 YR
	Race	Caucasian
	Ethnicity	Hispanic or Latino
	Publications Cited	0
	dbGap	No
	Biopsy Source	Blood
	Collection	Alzheimer’s Disease
	Cell Type	Stem Cell
	Tissue Type	Induced pluripotent stem cell
	Transformant	Episomal
	Species	sapiens
	Common Name	human
	Detailed Clinical Data	false
Clinical data (source: CIRM)	AlzheimersDisease	AlzheimersDisease
	Typical_probable_AD_diagnosis	Yes
	Age_at_onset_of_dementia	58
	Atypical_probable_AD:_Progressive aphasia	No
	Atypical_probable_AD:_Posterior cortical_atrophy	No
	APOE_e4_carrier	Yes
	Amyloid_biomarker_test_conducted_(CSF_or_amyloid_P	Yes
	Height_(inches)	59
	Weight_(pounds)	136

Users do not need any additional license for the use of these differentiated cells even when cells are used for high throughput screening or drug discovery.
All donor consents include statements on the following:
- Testing the cells’ DNA (this is referred to as the cell’s genetic code or sequence) and making the information known to other researchers
- Changing some of the genetic code or sequence within these cells
- Using cells to test or select drugs to treat disease
- Transplanting cells or resulting products to humans or animals
  Distributing cells widely (nationally and internationally) for research, training or commercial medical product development
- Future research and uses unforeseen at this time
Donors were screened and negative for HIV, HBV, and HCV. Donors under the age of 18 could opt out of HIV testing; all HCV-positive donors submitted skin punches, not peripheral blood, and were not screened for any infectious agents due to small volume of blood present in punches.
Human induced pluripotent stem cells were established by non-integrating episomal reprogramming. Reprogramming and quality control were performed by Cellular Dynamics International.